Fresh off winning Best Picture and Best Director for Nomadland at this year’s Academy Awards, Chloé Zhao returns to theaters with The Eternals. Her entry [...] The post Chloé Zhao’s ‘Eternals’ Drops First Look Teaser first appeared on PRP Breaking News and Top Stories.
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Friday, May 28, 2021
Phase 1 of CoinWind Token's ($COW) Initial DEX Offering on MDEX is a Spectacular Success
CoinWind, a DeFi (decentralized finance) smart yield aggregator launched its $COW token today. In an initial DEX offering (IDO) launched on three platforms - MDEX, WeStarter and Helmet, the yield aggregator offered 3.24 million $COW tokens for sale.
The listing was a huge success, with CoinWind tweeting to its 19K followers that the first phase of the IDO on MDEX (termed IMO - ‘Initial MDEX Offering’) lasted “only 10 seconds”.
The bulk of the tokens, 3 million $COW tokens, were made available on the MDEX platform. MDEX.COM is a leading DEX (decentralized exchange) that has captured major market share in recent months. The DEX uses a unique strategy of dual mining, combining liquidity and transaction mining, which has led to explosive growth in its transaction volumes.
The complete 3 million $COW tokens were scooped up on MDEX for the value of USD 1.5 million which was collected in the various token currencies (MDX, HT and BNB). A total of 8,874 wallet addresses participated.
Based on the HECO (Huobi Eco-Chain) and BSC (Binance Smart Chain) networks, as of this writing, the $COW token sale is reported to have amassed 64.63 million MDX on HECO, 47.85 million MDX on BSC, 9.25 million on the MDX/HT token pair liquidity pool and 1.14 million on the MDX/BNB token pair liquidity pool.
DeFi’s Explosive Growth
The DeFi market has exploded in popularity in 2021, growing from around USD 3 billion in total value locked to USD 80 billion in total value locked in 12 months. While the market has grown, some users have either struggled to get the best returns on their investments, or have been wary of entering the market because of a perception of increased risk in DeFi investing, which they believe could lead to a loss in capital.
A spokesperson for CoinWind, the team behind the $COW token, said the project solves both of these issues.
The CoinWind Solution to Low Returns and High Risk in DeFi Investing
By matching users' pledged tokens to maximize returns for all users, CoinWind promises to deliver stronger returns for users who want to farm their crypto assets.
“CoinWind works by automatically matching pledged tokens to high-yield pools for optimal returns,” says Musk, Head of CoinWind Community. “Furthermore, income generated is automatically reinvested every 5-10 minutes into high-yield projects, ensuring all income is used to generate profit, and no opportunity is lost. We also use hedging strategies to reduce impermanent losses.”
In DeFi investing, impermanent loss happens when the price of an investor’s tokens changes, as compared to the price of the tokens when they were first deposited in the pool.
Competitive Edge
By offering low user thresholds and maintaining high yields, CoinWind’s value proposition is to attract liquidity providers. The platform is particularly popular in China for single-token yield farming.
CoinWind offers both single-token (or single-asset) and LP (liquidity pool) farming opportunities, offering attractive APY (annual percentage yield) with flexible staking.
CoinWind Tokenomics ($COW)
The total supply of $COW tokens is 100 million. Of this, 65% will be used to reward users for farming in CoinWind, with the output halved every year.
Fifteen percent is allocated for the team’s operations, technology research and development, which will be unlocked one month after launch for 12 months.
Ten percent is allocated for early investors, while the remaining 10% will be used for the community foundation, fundraising and marketing.
As the project grows, the CoinWind team plans to expand to more blockchains including Ethereum, OKChain, Solana and others.
For more info about CoinWind, visit the official website: https://www.coinwind.com
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Thursday, May 27, 2021
Ziqitza Limited Rajasthan - How effective are vaccines against Covid Mutant Variant?
With so many news headlines focusing on the variants and their potential to prolong the pandemic, it’s no wonder that people have become increasingly concerned that the vaccines won’t work as well against mutations.
But infectious disease doctors say that even if antibody levels drop in the months following vaccination, the immune system is complex and robust. We’ll be well protected against variants, they say, with a lower risk for disease, hospitalization, and death.
The key question is, just how well do the vaccines work against the variants?
According to experts, well enough that vaccinated people don’t need to worry too much about the current known variants. Ziqitza has gone through the data from vaccine clinical trials and real world evidence show that even in the face of variants, the coronavirus vaccines can prevent infection and drastically cut people’s chances of severe disease and hospitalization.
As everyone knows, there are two vaccines currently in use in our country. Dr Datar, Medical Director, Ziqitza Healthcare Ltd says they can prevent severe disease and death and definitely reduce infections. He further says after vaccination, if we get infection, it is known as breakthrough infection.
Only 0.02% to 0.04% – or two to four per 10,000 – of vaccinated persons saw breakthrough infections after Covid-19 vaccination, which is a very small number, but even these few infections could be explained partly by the higher exposure of the infected persons compared to the general population, and to the ongoing second surge in India.
In the midst of these variant discoveries, there are conflicting reports on vaccine efficacy. So, here’s a summary based on science of what we currently know, what we don’t know, and what we can infer. Let’s start by asking what exactly is immune escape? Should we worry about it? And what does it mean for those who are already vaccinated?
Variants of concerns are mutated forms of SARS-CoV-2 that are more infectious, can cause more severe disease, can evade some immune responses, or do any combination of the above. Immune escape variants have mutations that prevent them from being tagged by antibodies, generated either because of prior infection or due to vaccination.
Effective neutralizing antibodies can stick to specific parts of the spike protein on the virus, preventing it from attaching to the receptor on the cell. Therefore, antibodies have a major role to play in preventing infection, both after natural infection and vaccination.
Viruses naturally mutate. Over time, those mutations that help the virus to escape from the antibodies can be maintained since they confer a selective advantage.Because vaccines were not developed with variants in mind, the antibodies that result from the first generation of covid-19 vaccines might not be able to neutralize variants in similar numbers to earlier versions of SARS-CoV-2.
Ziqitza Limited says while there is much to learn about emerging variants and how vaccines work against them, there is already much that we know. Headlines on “immune escape” variants may indeed be alarming, but they are also simplistic. The immune system is analogous to a complex machine with many parts and settings. It isn’t a switch that goes between “on” and “off”.
The best way to examine the effect of variants on vaccine efficacy is in a well-designed clinical trial. Even in the absence of vaccination, severe disease is rarer in young populations. Another limitation of the trial is that it was small.In the absence of clinical trials in people, there are ways to test vaccines against variants in the laboratory. Researchers are currently reporting antibody numbers from test variants to detect possible “immune escape”.
Many of these laboratory tests check how well antibodies recognize and prevent variants from attaching to cells. Serum is the fluid component of blood that contains antibodies. It is taken from those who have been vaccinated and is tested against variants.
Some of these tests have demonstrated reduced neutralization in immune escape variants.
But these antibody neutralization tests have limitations because serum doesn’t contain T cells, memory B cells or plasma cells which are other important components of adaptive immunity in addition to antibodies. In short, it is very difficult to recapitulate what is happening in the body from laboratory tests because they don’t capture the entire landscape of human immunity.
As per the observation done by Ziqitza Limited Rajasthan so far, there have been no reports of widespread mortality in those who have been exposed to any lineage of SARS-CoV-2 after receiving both doses of any vaccine. This may change over time, but after hundreds of millions of vaccinations, this should be a cause of optimism. Vaccines are indeed saving lives.
The data from multiple studies indicates that we will need to continue monitoring the spread of variants through genomic surveillance, but vaccinations will play an important role in ending the pandemic. They may not prevent infection from certain variants of concern or even stop mild to moderate symptomatic covid-19, but to-date all data indicate that they are extremely effective in preventing severe infections.
In the future, updated booster shots tailored to specific variants could strengthen the immune response to variants. Researchers are looking into different approaches to combat variants right now, but the vaccines we have are powerful tools in reducing the healthcare burden of the pandemic. To sum up, all vaccines may not work equally well against all variants in preventing covid-19, but if they can keep people alive, they have met a primary objective.
Ziqitza Healthcare Ltd is Asia’s largest emergency medical service provider company and one of the fastest-growing holistic healthcare solution platforms in India. Be it Rural or Urban space ZHL Rajasthan & Ziqitza Limited Rajasthan has also contributed in saving more than 30 Million lives. Ziqitza Healthcare is also a pioneer in the ambulance services business in India, the vast experience and knowledge make it more viable to extend its services into this segment. Being a “one-stop solution” for corporate wellness & holistic healthcare for giant corporations, Ziqitza Limited also offers turnkey solutions that include Ambulance at the Site, Wellness at Workplace, Telehealth Services for Employees, Medical Rooms, Doctors on Site, and Occupational Health Therapies, among others. Ziqitza’s Corporate Wellness Programmes are designed to meet a variety of needs and requirements of any corporate entity – service, manufacturing, warehousing or construction site and offer customized holistic healthcare programs to all.
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ZHL Rajasthan - Things you should know about Double Masking
Strong evidence suggests that the SARS-CoV-2 virus is primarily airborne, what does this mean and can we change the way we protect ourselves?
Scientists and medical health practitioners have been highlighting the need to wear masks to contain the spread of coronavirus ever since the pandemic began.
A large population does not show symptoms. The asymptomatic people can continue to spread the infection at home, at a faster pace. Dr. Datar, Medical director of Ziqitza Healthcare Ltd stress that even when asymptomatic people are talking, they can spread the infection.That is why we have been seeing entire families, in this wave, turning positive, even when most of them have stayed indoors. So it’s not only imperative to wear mask outdoors but indoors too.
While there have been many cases of people taking this advice for granted and not wearing masks properly (by wearing it below their nose and so on), latest research has established that wearing two tightly-fitted face masks can nearly double the protection against the virus. As mask with layers offers better protection, as it creates a stronger barrier for respiratory droplets.
Ziqitza Rajasthan and ZHL Rajasthan says as Covid-19 cases are rising rapidly across the country, it is becoming more and more essential to adopt the most effective safety practices to avoid getting infected. When a person wears one mask on top of another, it is termed as double masking. The outer mask can apply gentle pressure on the edges of the inner mask and creates a better seal. Since the virus spread through respiratory droplets, two layers can help to increase filtration and can provide you with better protection.
How to wear double masks properly?
According to multiple studies conducted by the US CDC, double masks can prove to be very effective in preventing the spread of COVID-19. However, this is only applicable when you wear the double mask properly.
There are three ways of wearing double masks properly.
1. Using a surgical mask with a cloth mask
Cloth masks alone are not recommended, but pairing them with a surgical mask drastically increases the effectiveness.Doing this is very simple, too. First, wear the surgical mask and then the cloth mask on top of it.CDC suggests that the cloth mask should push the edges of the surgical mask against your face. In simple words, the cloth mask should offer a tight, snug fit.
2. Pick a mask with nose wires
Another important aspect to consider while choosing a face mask is that it should have a nose wire. Ziqitza Limited adds by saying a good quality surgical masks come with an embedded nose wire on one side. When you wear the mask, push the nose wire so it closes any gaps that may be present.Some other masks come with a metal wire, which offers an even more snug fit.
3. Knotting the ear loops of a 3-ply surgical mask
Knot the ear loops of a 3-ply face mask where they join the edge of the mask and then Fold and tuck the unneeded material under the edges
Ziqitza Healthcare suggests to avoid combinations of the following Masks:
1. Combining two surgical masks as they are not designed to fit tightly.
2. Combining KN95 and any other type of mask
3. Combining a N95 mask with any other mask.
Before stepping out while wearing 2 masks check for things like:
1. Fit: Make sure that the outer mask helps press the inner mask close to your face, forming a seal. To do this, cup your hands over your mask and feel for air escaping from the edges as you breathe.
2. Breathing: While breathing may require a little extra effort when you’re double masking, it shouldn’t make breathing difficult.
3. Vision: Make sure that your double mask doesn’t block your vision.
4. Evaluate the situation: you can maintain a distance of at least 6 feet from others outside your household; a single mask can give good protection. However, a double mask can be more beneficial.
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Auburn rises in latest CBS Sports preseason college basketball rankings
Auburn Arena is going to be loud once again this season as the Tigers return to likely a full house in front of one of [...] The post Auburn rises in latest CBS Sports preseason college basketball rankings first appeared on PRP Breaking News and Top Stories.
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New COVID-19 Cases Haven’t Been This Low In The U.S. Since Last June
New coronavirus cases across the United States have tumbled to rates not seen in more than 11 months, sparking optimism that vaccination campaigns are stemming [...] The post New COVID-19 Cases Haven’t Been This Low In The U.S. Since Last June first appeared on PRP Breaking News and Top Stories.
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U.S. reports lowest number of new COVID-19 cases in nearly a year
The United States last week reported the lowest number of new COVID-19 cases in nearly a year, with new infections dropping 26% from the previous [...] The post U.S. reports lowest number of new COVID-19 cases in nearly a year first appeared on PRP Breaking News and Top Stories.
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